The Research Scientist – Immunology candidate will possess previous research experience in immunology, biotechnology and drug development. The ideal candidate will have a PhD in biotech, immunology, bioinformatics or related field be well-versed in common laboratory practices, skills, and techniques to support preclinical, translational, and clinical studies. This candidate will work closely with the Associate Director of Inflammation & Immunology and the Chief Scientific Officer (CSO) and other Research and Development team members in the development of first-in-class, oral therapeutics for the treatment of autoimmune diseases.
The candidate will be completely aligned with the four fundamental pillars of Landos’ entrepreneurial and efficient corporate culture: 1) Be bold and decisive, 2) Never give up, 3) Be solution-oriented, and 4) Do the impossible.
- Experimental Design: Generate and test novel experimental hypotheses to advance discovery-based R&D at Landos. Propose controlled designs capable of robustly testing respective hypotheses to draw conclusions relevant to drug development research.
- Patents and publications: Will develop independently patents and peer-reviewed publications thematically linked to Landos’ novel mechanisms of action and product candidate pipeline.
- Data analysis: Utilize established and novel methods to analyze data. Data types will include but are not limited to flow cytometry results, high-throughput sequencing, protein biochemistry assays, and histopathology.
- Data communication and reporting: Provide detailed reports of experimental results. Generate figures, presentations and publications to communicate results with scientific community, investors, and collaborators. Support the development of patents and grants relevant to on-going research.
- Laboratory Procedures: Perform various standard experimental assays including quantitative real-time PCR, Western blot, flow cytometry, and ELISA. Work in sterile conditions to conduct cell culture experiments and maintain the growth of cell lines. Express and purify recombinant protein. Collect and analyze generated data.
- Personnel Training: Training of Landos personnel on laboratory upkeep, experimental assays and research projects. Guide the personnel resourcing of projects and tasks.
- Animal Procedures: Conduct various IACUC approved laboratory animal procedures and techniques for Landos projects including but not limited to basic rodent handling, oral gavage, intraperitoneal injection, blood collection, and euthanasia. Interact with animal facility personnel to maintain organization and compliance of animal facilities.
- Teamwork: Work independently and collaboratively in a matrixed environment. Be able to successfully work with other Landos team members in experiments.
- Regulatory Compliance: Support regulatory compliance efforts as instructed by the senior leadership in accordance with IACUC, IBC, and IRB protocols. Implement, organize and maintain regulatory compliance records.
- Record keeping: Keep detailed records of all activities, record these activities in ASANA, Google Drive, laboratory notebook, the Landos Colony Management System (CMS), and Labkey. Provide weekly updates of the Landos research progress to the Scientific Director, and Landos team.
- Any new responsibilities or changes in the reporting structure as directed by the Landos leadership.
- Maintains the strictest confidentiality of all activities.
- Team player, engendering credibility and confidence within and outside the company.
- Faithfully performs any other tasks requested by the Chairman, President & CEO.
- Act in accordance with Landos’ policies and in alignment with the corporate culture.